Some research has suggested that consumption of high-fructose corn syrup, used as a sweetener in a wide variety of foods, may increase the risk of obesity and heart disease. Now, a controlled and randomized study has found that drinks sweetened with fructose led to higher blood levels of L.D.L, or “bad” cholesterol, and triglycerides in overweight test subjects, while drinks sweetened with another sugar, glucose, did not. Both L.D.L. and triglycerides have been linked to an increased risk of cardiovascular disease.
The study was published online on Monday in The Journal of Clinical Investigation.